Found throughout the Tallgrass Prairie region in native prairies and prairie remnants on dry or well-drained soils. Often found with P. purpureum. Blooms from May to September. Not a typical legume flower, having one large petal and four smaller ones. The tiny flowers grow tightly together on the cone at the top of the stem.

This was one of the favored plants of the Native Americans of the prairies. A tea made from the leaves was applied to open wounds and a tea made from the bruised leaves steeped in hot water was used to aid in the healing of wounds as well. Some tribes pulverized the root and made a tea from that powder that was a very healthy drink and a preventative medicine. Some tribes used the entire plant as a prophylactic (medicine which preserves or defends against disease; a preventive). Early settlers mixed the bark of the white oak tree and the flowers of this species to make a medicine for diarrhea. The Ponca tribe was known to chew the roots of prarie clover simply for the pleasant taste. Native American women also gathered the stems of prairie clover and made brooms and brushes from them when dried. The Pawnee name for this species literally translates as "broom-weed".

In Europe, especially in Ireland and Scotland, the seeds of prairie clover were ground into a flour. The flour made a very tasty and highly nutritous bread.

Edible Uses: Root - raw or chewed for its pleasant sweet flavour]. Eaten as a delicacy by children. A tea-like beverage is made from the dried leaves.

Medicinal Uses: The roots have been chewed to bring relief from the pain.

Herbal Uses: Unknown